Found 11 matching trials
A Screening Study Targeting Tumor-specific Antigens N/A The purpose of this study is to identify patients who may be eligible to pa...
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Miami Cancer Institute
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Personalized Neoantigen Vaccine in Combination With Durvalumab (MEDI4736) in Extensive Stage Small Cell Lung Cancer PHASE2 The investigators hypothesize that a personalized neoantigen vaccine combin...
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Active Not Recruiting
Location
Washington University School of Medicine
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GNOS-PV02 Personalized Neoantigen Vaccine, INO-9012 and Pembrolizumab in Subjects With Advanced HCC PHASE1 This is a single-arm, open-label, multi-site Phase I/IIa study of a persona...
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Active Not Recruiting
Location
Johns Hopkins Hospital
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Neoantigen-based Personalized DNA Vaccine With Retifanlimab PD-1 Blockade Therapy in Patients With Newly Diagnosed, Unmethylated Glioblastoma PHASE1 This is a single institution, open-label, multi-arm, phase I study assessin...
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Active Not Recruiting
Location
Washington University School of Medicine
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Neoantigen DNA Vaccine in Pancreatic Cancer Patients Following Surgical Resection and Adjuvant Chemotherapy PHASE1 This is a phase 1 open-label study to evaluate the safety and immunogenicit...
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Johns Hopkins School of Medicine
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Study Evaluating the Safety Feasibility and Efficacy of ODI-2001 Vaccine, a Personnalized Immunotherapy in Patients With Metastatic or Locally Advanced Colon Cancer or Pancreatic Cancer PHASE1 This is a phase 1, open-label, multicentric study evaluating the safety, fe...
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Neoepitope-based Personalized DNA Vaccine Approach in Pediatric Patients With Recurrent Central Nervous System Tumors PHASE1 The purpose of this research study is to learn about the safety and feasibi...
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Washington University School of Medicine
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NECVAX-NEO1 in Addition to Checkpoint Inhibitor in Patients With Solid Tumors PHASE1 NECVAX-NEO1 in addition to anti-PD-1 or anti-PD-L1 monoclonal antibody chec...
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Active Not Recruiting
Location
Kaunas University Hospital
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Clinical Study of the Therapeutic Effectiveness of In-silico-Designed, Machine Learning Inspired, and Quantum-molecularly Coupled Personalized Neoantigenic Vaccines Microlyvaq™ in Patients With Advanced Non-small Cell Lung Cancer EARLY_PHASE1 Microlyvaq™ is a first-line, non-randomized, two-arm clinical trial in adva...
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Enrolling By Invitation
Location
Biogenea Pharmaceuticals Ltd
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Personalized Neoantigen Vaccine Plus IL-12 (INO-9012) Versus Active Surveillance in Subjects With High-Risk HCC PHASE2 This is a randomized, open-label, multi-site Phase II study of a personaliz...
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